Deupí, Xavier : rechercher sur Z-Library

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1

Molecular signatures of G-protein-coupled receptors

Venkatakrishnan, A. J., Deupi, Xavier, Lebon, Guillaume, Tate, Christopher G., Schertler, Gebhard F., Babu, M. Madan

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 2.16 MB

english, 2013

2

Structural Models of Class A G Protein-Coupled Receptors as a Tool for Drug Design: Insights on Transmembrane Bundle Plasticity

Deupi, Xavier, Dolker, Nicole, Luz Lopez-Rodriguez, Maria, Campillo, Mercedes, Ballesteros, Juan, Pardo, Leonardo

Journal:

Current Topics in Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 341 KB

english, 2007

3

The Role of Internal Water Molecules in the Structure and Function of the Rhodopsin Family of G Protein-Coupled Receptors

Leonardo Pardo, Xavier Deupi, Nicole Dölker, María Luz López-Rodríguez, Mercedes Campillo

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 522 KB

english, 2007

4

Ligand-regulated oligomerization of β2-adrenoceptors in a model lipid bilayer

Fung, Juan José, Deupi, Xavier, Pardo, Leonardo, Yao, Xiao Jie, Velez-Ruiz, Gisselle A, DeVree, Brian T, Sunahara, Roger K, Kobilka, Brian K

Journal:

The EMBO Journal

Année:

2009

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2009

5

Tracking G-protein-coupled receptor activation using genetically encoded infrared probes

Schertler, Gebhard F. X., Sakmar, Thomas P., Deupi, Xavier, Vogel, Reiner, Ye, Shixin, Zaitseva, Ekaterina, Caltabiano, Gianluigi

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 799 KB

english, 2010

6

Coupling ligand structure to specific conformational switches in the β2-adrenoceptor

Yao, Xiaojie, Parnot, Charles, Deupi, Xavier, Ratnala, Venkata R P, Swaminath, Gayathri, Farrens, David, Kobilka, Brian

Journal:

Nature Chemical Biology

Année:

2006

Langue:

english

Fichier:

PDF, 324 KB

english, 2006

7

Conserved activation pathways in G-protein-coupled receptors

Deupi, Xavier, Standfuss, Jörg, Schertler, Gebhard

Journal:

Biochemical Society Transactions

Année:

2012

Langue:

english

Fichier:

PDF, 338 KB

english, 2012

8

The activation mechanism of chemokine receptor CCR5 involves common structural changes but a different network of interhelical interactions relative to rhodopsin

Jean-Yves Springael, Cédric de Poorter, Xavier Deupi, Joost Van Durme, Leonardo Pardo, Marc Parmentier

Journal:

Cellular Signalling

Année:

2007

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2007

9

Structural insights into agonist-induced activation of G-protein-coupled receptors

Xavier Deupi, Jörg Standfuss

Journal:

Current Opinion in Structural Biology

Année:

2011

Langue:

english

Fichier:

PDF, 1004 KB

english, 2011

10

Influence of the g− conformation of Ser and Thr on the structure of transmembrane helices

Xavier Deupi, Mireia Olivella, Arantxa Sanz, Nicole Dölker, Mercedes Campillo, Leonardo Pardo

Journal:

Journal of Structural Biology

Année:

2010

Langue:

english

Fichier:

PDF, 551 KB

english, 2010

11

Characterization of a conformationally sensitive TOAC spin-labeled substance P

Aaron M. Shafer, Clovis R. Nakaie, Xavier Deupi, Vicki J. Bennett, John C. Voss

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2008

12

Ligands Stabilize Specific GPCR Conformations: But How?

Xavier Deupi, Xiao-Dan Li, Gebhard F.X. Schertler

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 66 KB

english, 2012

13

Conformational complexity of G-protein-coupled receptors

Brian K. Kobilka, Xavier Deupi

Journal:

Trends in Pharmacological Sciences

Année:

2007

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2007

14

[Advances in Protein Chemistry] Mechanisms and Pathways of Heterotrimeric G Protein Signaling Volume 74 || Activation of G Protein–Coupled Receptors

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

15

Serine and Threonine Residues Bend α-Helices in the χ1=g− Conformation

Ballesteros, Juan A., Deupi, Xavier, Olivella, Mireia, Haaksma, Eric E.J., Pardo, Leonardo

Journal:

Biophysical Journal

Année:

2000

Langue:

english

Fichier:

PDF, 336 KB

english, 2000

16

Influence of the Environment in the Conformation of α-Helices Studied by Protein Database Search and Molecular Dynamics Simulations

Olivella, Mireia, Deupi, Xavier, Govaerts, Cedric, Pardo, Leonardo

Journal:

Biophysical Journal

Année:

2002

Langue:

english

Fichier:

PDF, 166 KB

english, 2002

17

Ser and Thr Residues Modulate the Conformation of Pro-Kinked Transmembrane α-Helices

Deupi, Xavier, Olivella, Mireia, Govaerts, Cedric, Ballesteros, Juan Antonio, Campillo, Mercedes, Pardo, Leonardo

Journal:

Biophysical Journal

Année:

2004

Langue:

english

Fichier:

PDF, 558 KB

english, 2004

18

Insights into congenital stationary night blindness based on the structure of G90D rhodopsin

Singhal, Ankita, Ostermaier, Martin K, Vishnivetskiy, Sergey A, Panneels, Valérie, Homan, Kristoff T, Tesmer, John J G, Veprintsev, Dmitry, Deupi, Xavier, Gurevich, Vsevolod V, Schertler, Gebhard F X,

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1.87 MB

english, 2013

19

Molecular dynamics: A stitch in time

Journal:

Nature Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 174 KB

english, 2013

20

Relevance of rhodopsin studies for GPCR activation

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Année:

2014

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2014

21

Retinal proteins — You can teach an old dog new tricks

Heberle, Joachim, Deupi, Xavier, Schertler, Gebhard

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Année:

2014

Langue:

english

Fichier:

PDF, 201 KB

english, 2014

22

A Microsecond Time Scale Molecular Dynamics Simulation of B2AR in a Membrane

Romo, Tod D., Grossfield, Alan, Pitman, Michael C., Deupi, Xavier, Cordomi, Arnau, Kobilka, Brian

Journal:

Biophysical Journal

Année:

2009

Langue:

english

Fichier:

PDF, 106 KB

english, 2009

23

Structural and Functional Characterization of Alternative Transmembrane Domain Conformations in VEGF Receptor 2 Activation

Manni, Sandro, Mineev, Konstantin S., Usmanova, Dinara, Lyukmanova, Ekaterina N., Shulepko, Mikhail A., Kirpichnikov, Mikhail P., Winter, Jonas, Matkovic, Milos, Deupi, Xavier, Arseniev, Alexander S.,

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 2.51 MB

english, 2014

24

Functional map of arrestin-1 at single amino acid resolution

Ostermaier, Martin K., Peterhans, Christian, Jaussi, Rolf, Deupi, Xavier, Standfuss, Jörg

Journal:

Proceedings of the National Academy of Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2014

25

Probing Gαi1 protein activation at single–amino acid resolution

Sun, Dawei, Flock, Tilman, Deupi, Xavier, Maeda, Shoji, Matkovic, Milos, Mendieta, Sandro, Mayer, Daniel, Dawson, Roger J P, Schertler, Gebhard F X, Babu, M Madan, Veprintsev, Dmitry B

Journal:

Nature Structural and Molecular Biology

Année:

2015

Langue:

english

Fichier:

PDF, 2.74 MB

english, 2015

26

TMalphaDB and TMbetaDB: web servers to study the structural role of sequence motifs in α-helix and β-barrel domains of membrane proteins

Perea, Marc, Lugtenburg, Ivar, Mayol, Eduardo, Cordomí, Arnau, Deupí, Xavier, Pardo, Leonardo, Olivella, Mireia

Journal:

BMC Bioinformatics

Année:

2015

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2015

27

Batch crystallization of rhodopsin for structural dynamics using an X-ray free-electron laser

Wu, Wenting, Nogly, Przemyslaw, Rheinberger, Jan, Kick, Leonhard M., Gati, Cornelius, Nelson, Garrett, Deupi, Xavier, Standfuss, Jörg, Schertler, Gebhard, Panneels, Valérie

Journal:

Acta Crystallographica Section F Structural Biology Communications

Année:

2015

Langue:

english

Fichier:

PDF, 857 KB

english, 2015

28

Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor

Isogai, Shin, Deupi, Xavier, Opitz, Christian, Heydenreich, Franziska M., Tsai, Ching-Ju, Brueckner, Florian, Schertler, Gebhard F. X., Veprintsev, Dmitry B., Grzesiek, Stephan

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 4.89 MB

english, 2016

29

Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region

Venkatakrishnan, A. J., Deupi, Xavier, Lebon, Guillaume, Heydenreich, Franziska M., Flock, Tilman, Miljus, Tamara, Balaji, Santhanam, Bouvier, Michel, Veprintsev, Dmitry B., Tate, Christopher G., Sche

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 8.21 MB

english, 2016

30

Structural role of the T94I rhodopsin mutation in congenital stationary night blindness

Singhal, Ankita, Guo, Ying, Matkovic, Milos, Schertler, Gebhard, Deupi, Xavier, Yan, Elsa CY, Standfuss, Joerg

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2016

31

Convergent evolution of tertiary structure in rhodopsin visual proteins from vertebrates and box jellyfish

Gerrard, Elliot, Mutt, Eshita, Nagata, Takashi, Koyanagi, Mitsumasa, Flock, Tilman, Lesca, Elena, Schertler, Gebhard F. X., Terakita, Akihisa, Deupi, Xavier, Lucas, Robert J.

Journal:

Proceedings of the National Academy of Sciences

Année:

2018

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2018

32

Molecular Basis of Ligand Dissociation in β-Adrenergic Receptors

González, Angel, Perez-Acle, Tomas, Pardo, Leonardo, Deupi, Xavier, van Veen, Hendrik W.

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2011

33

The DRF motif of CXCR6 as chemokine receptor adaptation to adhesion

Koenen, Andrea, Babendreyer, Aaron, Schumacher, Julian, Pasqualon, Tobias, Schwarz, Nicole, Seifert, Anke, Deupi, Xavier, Ludwig, Andreas, Dreymueller, Daniela, Eugenin, Eliseo A.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 2.26 MB

english, 2017

34

GPCR-SAS: A web application for statistical analyses on G protein-coupled receptors sequences

Gómez Tamayo, José Carlos, Olivella, Mireia, Ríos, Santiago, Hoogstraat, Marlous, Gonzalez, Angel, Mayol, Eduardo, Deupi, Xavier, Campillo, Mercedes, Cordomí, Arnau, Porollo, Alexey

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 6.46 MB

english, 2018

35

Crystal structure of rhodopsin in complex with a mini-G o sheds light on the principles of G protein selectivity

Tsai, Ching-Ju, Pamula, Filip, Nehmé, Rony, Mühle, Jonas, Weinert, Tobias, Flock, Tilman, Nogly, Przemyslaw, Edwards, Patricia C., Carpenter, Byron, Gruhl, Thomas, Ma, Pikyee, Deupi, Xavier, Standfuss

Journal:

Science Advances

Année:

2018

Langue:

english

Fichier:

PDF, 1.79 MB

english, 2018

36

Arrestin-1 engineering facilitates complex stabilization with native rhodopsin

Haider, Raphael S., Wilhelm, Florian, Rizk, Aurélien, Mutt, Eshita, Deupi, Xavier, Peterhans, Christian, Mühle, Jonas, Berger, Philipp, Schertler, Gebhard F. X., Standfuss, Jörg, Ostermaier, Martin K.

Journal:

Scientific Reports

Année:

2019

Fichier:

PDF, 2.91 MB

2019

37

Elucidating the structure-activity relationship of the pentaglutamic acid sequence of minigastrin with the cholecystokinin receptor subtype 2

Ritler, Andreas, Shoshan, Michal, Deupi, Xavier, Wilhelm, Patrick, Schibli, Roger, Wennemers, Helma, Behe, Martin

Journal:

Bioconjugate Chemistry

Année:

2019

Langue:

english

Fichier:

PDF, 571 KB

english, 2019

38

The Two-Photon Reversible Reaction of the Bistable Jumping Spider Rhodopsin-1

Ehrenberg, David, Varma, Niranjan, Deupi, Xavier, Koyanagi, Mitsumasa, Terakita, Akihisa, Schertler, Gebhard F.X., Heberle, Joachim, Lesca, Elena

Journal:

Biophysical Journal

Année:

2019

Fichier:

PDF, 1.12 MB

2019

39

The Two-Photon Reversible Reaction of the Bistable Jumping Spider Rhodopsin-1

Ehrenberg, David, Varma, Niranjan, Deupi, Xavier, Koyanagi, Mitsumasa, Terakita, Akihisa, Schertler, Gebhard F.X., Heberle, Joachim, Lesca, Elena

Journal:

Biophysical Journal

Année:

2019

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2019

40

Crystal structure of jumping spider rhodopsin-1 as a light sensitive GPCR

Varma, Niranjan, Mutt, Eshita, Mühle, Jonas, Panneels, Valérie, Terakita, Akihisa, Deupi, Xavier, Nogly, Przemyslaw, Schertler, Gebhard F. X., Lesca, Elena

Journal:

Proceedings of the National Academy of Sciences

Année:

2019

Langue:

english

Fichier:

PDF, 1.80 MB

english, 2019

41

Crystal structure of jumping spider rhodopsin-1 as a light sensitive GPCR

Varma, Niranjan, Mutt, Eshita, Mühle, Jonas, Panneels, Valérie, Terakita, Akihisa, Deupi, Xavier, Nogly, Przemyslaw, Schertler, Gebhard F. X., Lesca, Elena

Journal:

Proceedings of the National Academy of Sciences

Année:

2019

Fichier:

PDF, 1.80 MB

2019

42

The counterion–retinylidene Schiff base interaction of an invertebrate rhodopsin rearranges upon light activation

Nagata, Takashi, Koyanagi, Mitsumasa, Tsukamoto, Hisao, Mutt, Eshita, Schertler, Gebhard F. X., Deupi, Xavier, Terakita, Akihisa

Journal:

Communications Biology

Année:

2019

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2019

43

The counterion–retinylidene Schiff base interaction of an invertebrate rhodopsin rearranges upon light activation

Nagata, Takashi, Koyanagi, Mitsumasa, Tsukamoto, Hisao, Mutt, Eshita, Schertler, Gebhard F. X., Deupi, Xavier, Terakita, Akihisa

Journal:

Communications Biology

Année:

2019

Fichier:

PDF, 1.19 MB

2019

44

Triazolo-Peptidomimetics: Novel Radiolabeled Minigastrin Analogs for Improved Tumor Targeting

Grob, Nathalie M., HÃ¤ussinger, Daniel, Deupi, Xavier, Schibli, Roger, Behe, Martin, Mindt, Thomas L.

Journal:

Journal of Medicinal Chemistry

Année:

2020

Fichier:

PDF, 829 KB

2020

45

Distance-Dependent Cellular Uptake of Oligoproline-Based Homobivalent Ligands Targeting GPCRsâAn Experimental and Computational Analysis

Dobitz, Stefanie, Wilhelm, Patrick, Romantini, Nina, De Foresta, Martina, Walther, Cornelia, Ritler, Andreas, Schibli, Roger, Berger, Philipp, Deupi, Xavier, BÃ©hÃ©, Martin, Wennemers, Helma

Journal:

Bioconjugate Chemistry

Année:

2020

Fichier:

PDF, 1.66 MB

2020